Pet Health

In Part 1 of “37 Common Causes of Fever in Dogs”, Pet5H introduced us to causes related to common bacterial infections, dangerous infectious diseases & special infections, and parasitic diseases. In this Part 2, Pet5H continues to provide readers with detailed information about causes stemming from fungal diseases, poisoning and toxicity-related conditions, as well as metabolic, endocrine, and nutritional disorders.
IV. Fungal Diseases
Histoplasma Infection in Dogs
Histoplasmosis is an uncommon fungal infection in dogs, but when present, it can cause clinical signs such as chronic diarrhea, vomiting, irregular fever, and generalized debilitation. The Hepatomegaly and splenomegaly are frequently observed, and some cases may also exhibit jaundice or pneumonia. Diagnosis is often challenging due to its resemblance to other gastrointestinal disorders, but it can be confirmed through histopathological examination or analysis of body fluids.
Fever in Dogs Caused by Pulmonary Mycosis
Pulmonary fungal infections in dogs are most commonly caused by fungi like Blastomyces, Histoplasma, Aspergillus, or Cryptococcus species. Affected dogs often present with severe coughing, dyspnea, high fever, rapid weight loss, abdominal swelling, diarrhea, and vomiting. The disease typically progresses rapidly and can be fatal without appropriate antifungal therapy. Accurate identification of the causative fungus is essential, as different pathogens vary in virulence and antifungal susceptibility.
V. Toxic and Poisoning Conditions

Dog Fever from Lead Poisoning
Lead poisoning in dogs commonly presents with abnormal ocular and nasal discharge, tremors, paralysis, and recurrent seizures. Affected dogs may exhibit incessant barking, hypersalivation with frothing, epileptiform episodes, severe abdominal pain, and hematemesis or bloody diarrhea. In puppies, clinical signs are often more pronounced, including lethargy, dullness, emaciation, vision loss, and behavioral changes. On examination, severe gastritis and enteritis are typically observed, and a definitive diagnosis requires measurement of lead concentrations in body tissues or fluids.
Dog Fever from Strychnine Poisoning
Strychnine poisoning in dogs characterized by violent generalized seizures, sudden hyperthermia, and marked muscle rigidity. Spasms occur quickly and intensely, preventing normal movement. The combination of hyperthermia and severe neurological dysfunction can quickly become fatal without immediate emergency intervention. This highly dangerous intoxication most often results from accidental ingestion of rodenticide bait or contaminated food.
Fever in dogs is not just a simple reaction to external factors-it often signals an underlying health problem. Causes can range from common bacterial infections to serious contagious diseases such as hepatitis, leptospirosis, tetanus, or even anthrax.
Understanding the potential causes by disease group helps you recognize dangerous symptoms early and respond appropriately. If your dog experiences persistent fever along with warning signs such as vomiting, diarrhea, pus discharge, trembling, or seizures, it should never be ignored. Prompt veterinary examination and diagnostic testing are essential to identify the root cause, ensure effective treatment, and prevent life-threatening complications.
VI. Metabolic, Hormonal, and Nutritional Disorders

Dog Fever from Milk Fever (Puerperal Eclampsia)
Milk fever, also known as eclampsia or postpartum hypocalcemia, typically develops in lactating bitches within 2–3 weeks after whelping. Affected dogs appear restless, pant excessively with their tongue protruding, stagger, and suffer from recurrent seizures. Some show a characteristic posture with the head bent backward and may run in circles as if galloping. Body temperature can rise up to 42.2°C, and progressive weakness may lead to partial paralysis or coma. In severe cases, an uncontrolled reaction to calcium administration can trigger fatal shock.
Ketonemia in dogs (Ketoacidosis)
This is a serious condition commonly seen in diabetic dogs. When the body cannot utilize glucose as an energy source, it shifts to fat metabolism, producing byproducts known as ketones. Excessive accumulation of ketones can result in diabetic ketoacidosis (DKA), a life-threatening state of metabolic acidosis.
In the following section,Pet5H will highlight other overlooked but equally serious causes of fever that pose significant threats to your pet’s health. Stay with us!
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